Methanabol
Methanabol is a hexahydro-19-nor-4,9(alpha)-pregnadiene-3,17 dione. That is a synthetic anabolic steroid. It was first made in 1958 by German pharmaceutical company G.D. Searle & Company as Dianabol but its sale was later discontinued due to the patent expiring and generic forms becoming available as well as public awareness of its side effects. Methanabol differs from structurally similar steroids such as Anadrol or Dianoxyl 50 only with the addition of a double bond between positions 1 and 2 of the steroid backbone
History: Methanabol's first medical use was found on accident when some weightlifters getting drug OTC supplement from Mexico found it had been discontinued there. They then tried to order from another market that may have had more but was unable to due to a hurricane. While they were waiting for their insulin shipment at this drug store, a substitute pharmacist recommended Methanabol which was available as a veterinary steroid and it happened to be the only thing the customer could afford. When they started taking it instead of Dianoxyl 50, they saw great results with little negative impact on their health.
When G.D. Searle & Company made Dianabol in 1958, producer Wilhelm Steyger claimed its delivery form would allow oral administration without loss of anabolic activity at any point along the gastrointestinal tract from mouth to anus he also claimed that Dianabol is not affected by digestion or liver function. They claimed that due to its anabolic agents, it would have no androgenic side effects but all of the evidence suggests otherwise:
Methanabol has a very short half life (about 4 hours) therefore mixing it with olive oil in order to prolong its release is not possible since the steroid is excreted from the body so quickly.
A study involving sedentary men at rest found that when injected with 5mg/kg Methanabol (n=5) and then compared to their own baseline values ( n=5), they experienced significant elevations in Plasma LH, FSH, Prolactin and Testicular Androgens
When given 10mg to healthy men, there was no effect on androgen levels but after exercise (6 hours) the same group experienced a significant increase in androgens including: DHEA-S, Testosterone Androstanediol glucuronide
The body produces its own endogenous hormones; while Dianabol can increase protein synthesis and nitrogen retention that leads to muscle growth, other organs such as the prostate, seminal vesicles and other reproductive tissue may also grow. In many cases, this ends up causing an imbalance of sex hormone production due to over stimulation of the hypothalamic/pituitary axis which increases endogenous testosterone production.
In addition to affecting normal hormone function due to increased androgens & estrogenic activity it also decreases pituitary Gonadotropins LH and FSH which then reduces endogenous testosterone function. In one study, healthy men that were given 50mg Methanabol experienced a decrease of total plasma protein, albumin and fibrinogen levels. It also increased red blood cell count by 30% which can interfere with normal hematological parameters.
Side effects:
The side effects surrounding Methanabol (and other anabolic steroids) can vary based on the type used (orals vs ND), dosage, user's age / health status, personal genetics as well as other factors such as if they are taking any other drugs or medications at the same time or even certain foods they eat prior taking it all of which will influence the toxicity levels present with Methanabol. There are also legal prescription drugs that can be bought without needing a doctor's order and they contain the anabolic steroid Methandrostenolone, most of them use it in order to treat cases of muscle wasting diseases or AIDS patients.
Methanabol is one of the most toxic oral steroids known today due to its potential side effects including high estrogenic activity at elevated doses (although this does not seem to be as problematic when taken alone like Anadrol). Other common side effects include: oily skin, acne, body hair growth & increased aggression which may lead users to act more 'roid rage' type behavior.
One study found that taking low dosages (25-50mg) of Methanabol did not significantly affect blood pressure or kidney function but at higher dosages (100-150mg) it caused a significant decrease in creatinine clearance and significantly elevated both BUN & Albumin.
In another study, healthy men who were given 50mg/day of an oral steroid containing methandrostenolone for 12 weeks experienced a significant elevation in total cholesterol levels including LDL while also decreasing HDL levels which then increases the risk factors that can lead to cardiovascular disease.
A different study found out that Methanabol has a very high potential to cause liver toxicity since its 17alpha methyl groups makes it easily oxidized metabolically so it's difficult to detoxify using the liver. Other studies that have been done on rodents found out that Methanabol is a hepatocarcinogen which means it can cause liver tumors.
It's well known that anabolic steroids, in general, affect the level of blood coagulation factors naturally produced by the body so it should not be used before any surgery or during post operation recovery due to its ability to increase the risk of bleeding.
Large dosages (100mg+) can also cause significant suppression of testosterone production and release which is why high dosage users often use other drugs like HCG along with their steroid cycles to prevent testicular atrophy.
Taking high dosages of Methanabol (100mg+) can also negatively affect the users lipid profile.
Other side effects associated with Methanabol include: fatigue, headaches, nausea or vomiting, insomnia and depression. When taking very high doses (150mg+) it has the potential to cause liver damage which then affects its ability to properly process other hormones in the body including cholesterol & blood sugar levels.
If you are considering using Methandrostenolone for personal use, please note that it is not considered safe due to the dangerous side effects demonstrated above so if you want to take it please seek out a legal alternative such as Dianabol or Anadrol which will be safer than Methanabol.
Signs of Methanabol toxicity are typically excessive water retention, noticeable increases in body weight, accelerated hair loss for men & deepening of the voice in women. Men who are taking it may also notice enlarged breast tissue, testicular shrinkage and infertility when use is discontinued.
Please note that these side effects typically increase if several different anabolic steroids are used together due to the nature of increased estrogenic activity present with many other types which can then cause additional problems such as Gynecomastia. However it should be mentioned that Methandrostenolone has not been reported to cause any significant issues related to decreased sex drive or impotence so long as it is taken at reasonable dosages (25-50mg+ per day). Those who use the hormone only intermittently and for short durations (less than 12 weeks) may not need to worry about infertility or testicular issues if they discontinue use.
Because Methandrostenolone is known to decrease endogenous testosterone production, some users supplement with it on a cycle of anabolic steroids that already includes other compounds that stimulate natural testosterone production such as HCG & Clomid, while others use it in conjunction with post-cycle therapy (PCT) drugs like Nolvadex / Clomid by taking one dose after their last shot before beginning PCT. This will help protect against testicular atrophy caused by anabolic steroid use but will also inhibit gains made on that cycle - please consult with your physician before choosing a course of treatment.
Please be aware that this information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of Methandrostenolone is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug.
Some bodybuilders take doses as high as 400mg/day in order to speed up their muscle building process but this has been proven to be very dangerous and life shortening (due to its estrogenic effects). Because Methanabol aromatizes at such a high rate many users will also add Tamoxifen or Arimidex to their cycle in order to protect against this.
-However, research has shown that without the use of an anti-estrogen, Methanabol will increase estrogen levels by 1/3 more than other anabolic steroids like Dianabol (which is already known for its tendency to cause high estrogenic activity). The majority of users tend to find that the inclusion of Nolvadex & Clomid are two of the most effective means of countering Methanabol's estrogenic effects while still ensuring it remains effective at building muscle mass.
There are also some bodybuilders who prefer not to include any Arimidex or Tamoxifen with their Methandrostenolone doses but instead, stack it with other compounds such as Anavar (Oxandrolone) and Winstrol (Stanozolol) in order to keep estrogenic activity down. It should be noted however that this is not a safe practice and can cause liver damage without the use of an anti-estrogen like Arimidex or Nolvadex - please consult your physician before attempting any combination.
Methanabol has also been known to exhibit strong activity on the SHBG (Sex Hormone Binding Globulin), which limits its effectiveness at increasing muscle mass & strength by limiting free testosterone levels. Some users stack Methandrostenolone with substances such as Proviron for this purpose, both of which are very commonly found in many pre-contest stacks of many professional bodybuilders.
Methandrostenolone has also been shown to be weaker as an Anabolic agent than closely related compounds like Dianabol due to the fact that it doesn't bind well to the androgen receptor at low dosages, but appears to exert more of its anabolic effects on muscle tissue through non-genomic activity rather than by binding directly to androgen receptors.
It is thought that Methandienone binds so poorly to the androgen receptor because it lacks the 3-keto group required for interaction with this receptor, but some scientists believe that this steroid might produce some direct activation via some other mode of action.
History: Methanabol's first medical use was found on accident when some weightlifters getting drug OTC supplement from Mexico found it had been discontinued there. They then tried to order from another market that may have had more but was unable to due to a hurricane. While they were waiting for their insulin shipment at this drug store, a substitute pharmacist recommended Methanabol which was available as a veterinary steroid and it happened to be the only thing the customer could afford. When they started taking it instead of Dianoxyl 50, they saw great results with little negative impact on their health.
When G.D. Searle & Company made Dianabol in 1958, producer Wilhelm Steyger claimed its delivery form would allow oral administration without loss of anabolic activity at any point along the gastrointestinal tract from mouth to anus he also claimed that Dianabol is not affected by digestion or liver function. They claimed that due to its anabolic agents, it would have no androgenic side effects but all of the evidence suggests otherwise:
Methanabol has a very short half life (about 4 hours) therefore mixing it with olive oil in order to prolong its release is not possible since the steroid is excreted from the body so quickly.
A study involving sedentary men at rest found that when injected with 5mg/kg Methanabol (n=5) and then compared to their own baseline values ( n=5), they experienced significant elevations in Plasma LH, FSH, Prolactin and Testicular Androgens
When given 10mg to healthy men, there was no effect on androgen levels but after exercise (6 hours) the same group experienced a significant increase in androgens including: DHEA-S, Testosterone Androstanediol glucuronide
The body produces its own endogenous hormones; while Dianabol can increase protein synthesis and nitrogen retention that leads to muscle growth, other organs such as the prostate, seminal vesicles and other reproductive tissue may also grow. In many cases, this ends up causing an imbalance of sex hormone production due to over stimulation of the hypothalamic/pituitary axis which increases endogenous testosterone production.
In addition to affecting normal hormone function due to increased androgens & estrogenic activity it also decreases pituitary Gonadotropins LH and FSH which then reduces endogenous testosterone function. In one study, healthy men that were given 50mg Methanabol experienced a decrease of total plasma protein, albumin and fibrinogen levels. It also increased red blood cell count by 30% which can interfere with normal hematological parameters.
Side effects:
The side effects surrounding Methanabol (and other anabolic steroids) can vary based on the type used (orals vs ND), dosage, user's age / health status, personal genetics as well as other factors such as if they are taking any other drugs or medications at the same time or even certain foods they eat prior taking it all of which will influence the toxicity levels present with Methanabol. There are also legal prescription drugs that can be bought without needing a doctor's order and they contain the anabolic steroid Methandrostenolone, most of them use it in order to treat cases of muscle wasting diseases or AIDS patients.
Methanabol is one of the most toxic oral steroids known today due to its potential side effects including high estrogenic activity at elevated doses (although this does not seem to be as problematic when taken alone like Anadrol). Other common side effects include: oily skin, acne, body hair growth & increased aggression which may lead users to act more 'roid rage' type behavior.
One study found that taking low dosages (25-50mg) of Methanabol did not significantly affect blood pressure or kidney function but at higher dosages (100-150mg) it caused a significant decrease in creatinine clearance and significantly elevated both BUN & Albumin.
In another study, healthy men who were given 50mg/day of an oral steroid containing methandrostenolone for 12 weeks experienced a significant elevation in total cholesterol levels including LDL while also decreasing HDL levels which then increases the risk factors that can lead to cardiovascular disease.
A different study found out that Methanabol has a very high potential to cause liver toxicity since its 17alpha methyl groups makes it easily oxidized metabolically so it's difficult to detoxify using the liver. Other studies that have been done on rodents found out that Methanabol is a hepatocarcinogen which means it can cause liver tumors.
It's well known that anabolic steroids, in general, affect the level of blood coagulation factors naturally produced by the body so it should not be used before any surgery or during post operation recovery due to its ability to increase the risk of bleeding.
Large dosages (100mg+) can also cause significant suppression of testosterone production and release which is why high dosage users often use other drugs like HCG along with their steroid cycles to prevent testicular atrophy.
Taking high dosages of Methanabol (100mg+) can also negatively affect the users lipid profile.
Other side effects associated with Methanabol include: fatigue, headaches, nausea or vomiting, insomnia and depression. When taking very high doses (150mg+) it has the potential to cause liver damage which then affects its ability to properly process other hormones in the body including cholesterol & blood sugar levels.
If you are considering using Methandrostenolone for personal use, please note that it is not considered safe due to the dangerous side effects demonstrated above so if you want to take it please seek out a legal alternative such as Dianabol or Anadrol which will be safer than Methanabol.
Signs of Methanabol toxicity are typically excessive water retention, noticeable increases in body weight, accelerated hair loss for men & deepening of the voice in women. Men who are taking it may also notice enlarged breast tissue, testicular shrinkage and infertility when use is discontinued.
Please note that these side effects typically increase if several different anabolic steroids are used together due to the nature of increased estrogenic activity present with many other types which can then cause additional problems such as Gynecomastia. However it should be mentioned that Methandrostenolone has not been reported to cause any significant issues related to decreased sex drive or impotence so long as it is taken at reasonable dosages (25-50mg+ per day). Those who use the hormone only intermittently and for short durations (less than 12 weeks) may not need to worry about infertility or testicular issues if they discontinue use.
Because Methandrostenolone is known to decrease endogenous testosterone production, some users supplement with it on a cycle of anabolic steroids that already includes other compounds that stimulate natural testosterone production such as HCG & Clomid, while others use it in conjunction with post-cycle therapy (PCT) drugs like Nolvadex / Clomid by taking one dose after their last shot before beginning PCT. This will help protect against testicular atrophy caused by anabolic steroid use but will also inhibit gains made on that cycle - please consult with your physician before choosing a course of treatment.
Please be aware that this information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of Methandrostenolone is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug.
Some bodybuilders take doses as high as 400mg/day in order to speed up their muscle building process but this has been proven to be very dangerous and life shortening (due to its estrogenic effects). Because Methanabol aromatizes at such a high rate many users will also add Tamoxifen or Arimidex to their cycle in order to protect against this.
-However, research has shown that without the use of an anti-estrogen, Methanabol will increase estrogen levels by 1/3 more than other anabolic steroids like Dianabol (which is already known for its tendency to cause high estrogenic activity). The majority of users tend to find that the inclusion of Nolvadex & Clomid are two of the most effective means of countering Methanabol's estrogenic effects while still ensuring it remains effective at building muscle mass.
There are also some bodybuilders who prefer not to include any Arimidex or Tamoxifen with their Methandrostenolone doses but instead, stack it with other compounds such as Anavar (Oxandrolone) and Winstrol (Stanozolol) in order to keep estrogenic activity down. It should be noted however that this is not a safe practice and can cause liver damage without the use of an anti-estrogen like Arimidex or Nolvadex - please consult your physician before attempting any combination.
Methanabol has also been known to exhibit strong activity on the SHBG (Sex Hormone Binding Globulin), which limits its effectiveness at increasing muscle mass & strength by limiting free testosterone levels. Some users stack Methandrostenolone with substances such as Proviron for this purpose, both of which are very commonly found in many pre-contest stacks of many professional bodybuilders.
Methandrostenolone has also been shown to be weaker as an Anabolic agent than closely related compounds like Dianabol due to the fact that it doesn't bind well to the androgen receptor at low dosages, but appears to exert more of its anabolic effects on muscle tissue through non-genomic activity rather than by binding directly to androgen receptors.
It is thought that Methandienone binds so poorly to the androgen receptor because it lacks the 3-keto group required for interaction with this receptor, but some scientists believe that this steroid might produce some direct activation via some other mode of action.
Methanabol Tablets Review
100 tabs 10mg/tab • methandrostenolone methandienone by British Dragon
Methanabol Tablets by British Dragon
Methanabol tablets are oral steroids and can affect protein metabolism in the body. This steroid is derived from testosterone and has tough androgenic and anabolic properties. It initiates protein synthesis and has extra ordinary effect on protein metabolism. This effect triggers positive nitrogen stability helping in building up of protein and thus builds up skeletal muscle mass.
Methanabol (Dianabol) is one of the most famous anabolic steroids for sale obtainable. Dianabol – Methanabol’s fame comes from its ability to give immediate anabolic results. A casual dose of 20 mg to 30 mg a day is sufficient to provide one with stunning Dianabol results. It is basically mixed with Testosterone Enanthate and Deca Durabolin steroids. In spite of heavy anabolic effects there are usual androgenic problems that erupt sometimes. But overall the users are satisfied with its usefulness. With Dianabol–Methanabol one can see high increase in strength and size. The Dianabol for sale online enhances glycogen retention and endurance capability.
The drawback that Dianabol–Methanabol brings is that it has innumerable side effects. It consists of alkylated 17 compounds, which is very poisonous to the liver. Average dose of Dianabol-Methanabol is 15mg to 30 mg daily orally or 50 mg to 100mg weekly in injectable form. Athletes and body builders across the globe regard Dianabol–Methanabol as the most efficient oral steroid ever manufactured. “Breakfast of Champions” is a right name for this steroid. Dianabol–Methanabol holds a second position to Anadrol cycles as being the most efficient mass and strength enhancing oral steroids but it is not harsh on the system as an Anadrol cycle.
Indications:
Appetite stimulant, increases mass of the muscles, increases red blood cells and increases bone density.
Presentation:
The manufacturer of Dianabol (Methanabol) is British Dragon, a Thailand firm. It comes in loose packs of 100 tabs or in original packs of 500 tabs each. Each tablet consists 1110 mg of Methandrostenolone.
Dbol Side Effects
While it is true that Dbol provides excellent bulking benefits, it is imperative that you use it responsibly in order to avoid the side effects. As far as anabolic steroids are concerned, Dbol boasts some of the mildest side effects when used as intended. Learning more about them, including what they are and why they exist, will help you avoid them.
The Effects of Dbol on Your Hormones
Dbol is a derivative of testosterone. In fact, it actually is testosterone, but it has one fewer carbon atom. As such, it binds to receptors in the body in the exact same way as testosterone but its modification produces different effects. For this reason, the body believes it no longer needs to produce testosterone. After all, according to the androgen receptors, there is plenty to go around. What's more, the Dbol converts to estrogen in the body, and this leads to excessive levels of female hormones. When you have too much estrogen and not enough testosterone in your body, symptoms are sure to arise.
Too Much Estrogen
What is the big deal about having too much estrogen in your body, anyway? When men have an abundance of estrogen in their bloodstreams, female characteristics begin to develop. You may notice that you are grouchy, tired, depressed, and plain irritable, but this is just the beginning. Over time, as the estrogen continues to build up, your facial hair may stop growing. You may actually gain weight as fat. You might even develop female breast tissue in a condition known as gynecomastia. The best way to prevent these Dbol side effects is to take only the recommended dose along with an aromatase inhibitor such as Arimidex or letrozole, which prevents the estrogen conversion from occurring.
Too Little Testosterone
There is actually a medical condition known as Low-T in which men have subpar levels of testosterone in their bodies. Some of the symptoms they encounter mimic Dbol side effects very closely. If you have low testosterone, you may notice that you have trouble getting or keeping an erection. You may experience extreme fatigue and moodiness, and you may lose your libido altogether. Over time, as the symptoms progress, you may experience testicular atrophy, or a condition in which the testicles shrink in size and your sperm count (and motility) drops significantly. All of these things are avoidable with a testosterone supplement or base during your cycles.
Milder Side Effects
Like any medication or drug, some Dianabol side effects, while bothersome, often produce no need for concern. One of these is water retention, which is another term for bloating. This often increases during the first week but begins to dissipate during the second week of your cycle. The other is oily skin, and the unfortunate thing is that you can do very little to prevent this. Using an acne medication may help keep blemishes at bay, however.
The Real Culprit: Liver Damage
Dozens of medications damage the liver, and Dbol is no exception. Although the noticeable Dbol side effects are mild, most people are not even aware that they have liver damage until it becomes severe. Do not take Dbol in its injected or tablet form with other oral steroids if you are concerned about liver damage. This increases the risk. It is also important to avoid alcohol during your cycles since it alone causes significant damage to your liver and the two together could prove disastrous.
In short, if you experience any of these side effects, it is best to lower your dose to a tolerable level. Some Dbol side effects, especially oily skin and moderately high blood pressure, may resolve themselves on their own after a day or two. Others, such as liver damage and gynecomastia, may become permanent if not dealt with promptly.